May play a role during development(By similarity). Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm, Nucleus
Clonality
polyclonal
Description
May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Host
Rabbit
Immunogen
WD repeat domain 18
Isotype
IgG
Molecular Weight
47 kDa
Reactivity
Human
Regulatory
RUO
Subcellular Location
Cytoplasm, Nucleus
Synonyms
R32184_1, WD repeat domain 18, WDR18
Antigen
WDR18
Uniprot
Q9BV38
Gene Id
57418
Research Area
Cell Division and Proliferation
Weight
47kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)