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Home / Primary Antibodies / Polyclonal Antibodies

WDFY3 antibody

SKU : BHA10809453

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Mfr.No.	FNab09479
Alternative Names	ALFY ; AutophagylinkedFYVEprotein ; KIAA0993 ; WDFY3 ; ZFYVE25
Background	Required for selective autophagy(aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies(p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Membrane, Nucleus
Clonality	polyclonal
Description	Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
Host	Rabbit
Immunogen	WD repeat and FYVE domain containing 3
Isotype	IgG
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Membrane, Nucleus
Synonyms	ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25

Uniprot	Q8IZQ1
Gene Id	23001
Research Area	Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC

Description

ELISA ; IHC

Dilution

IHC	1:20-1:200

Tested Application

IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809453	FNab09479	100ug	$260		Add to Cart

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