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Home / Primary Antibodies / Polyclonal Antibodies

VPS53 antibody

SKU : BHA10809422

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Mfr.No.	FNab09448
Alternative Names	FLJ10979 ; HCCS1 ; hVps53L ; pp13624 ; VPS53
Background	Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
Host	Rabbit
Immunogen	vacuolar protein sorting 53 homolog
Isotype	IgG
Molecular Weight	96 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	FLJ10979, HCCS1, hVps53L, pp13624, VPS53

Antigen	VPS53
Uniprot	Q5VIR6
Gene Id	55275
Research Area	Signal Transduction
Weight	96kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000
IP	1:200-1:2000

Tested Application

WB: 1:500-1:5000?IP: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809422	FNab09448	100ug	$260		Add to Cart

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