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Home / Primary Antibodies / Polyclonal Antibodies

VPS33B antibody

SKU : BHA10809411

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Mfr.No.	FNab09436
Alternative Names	FLJ14848 ; hVPS33B ; VPS33B
Background	May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity).
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic Vesicle, Endosome, Lysosome Membrane, Membrane
Clonality	polyclonal
Description	May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity).
Host	Rabbit
Immunogen	vacuolar protein sorting 33 homolog B(yeast)
Isotype	IgG
Molecular Weight	71 kDa
Reactivity	Human, Mouse, Rat, Zebrafish
Regulatory	RUO
Subcellular Location	Cytoplasmic vesicle, Endosome, Lysosome, Membrane
Synonyms	FLJ14848, hVPS33B, VPS33B

Uniprot	Q9H267
Gene Id	26276
Research Area	Signal Transduction
Weight	71kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:500-1:5000
IHC	1:50-1:200
IF	1:10-1:100

Tested Application

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

Manual	FNab09436.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809411	FNab09436	100ug	$240		Add to Cart

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