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Home / Primary Antibodies / Polyclonal Antibodies

UNC13A/Munc13-1 antibody

SKU : BHA10809244

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Mfr.No.	FNab09255
Alternative Names	KIAA1032 ; Munc131 ; Proteinunc13homologA ; unc13homologA(C.elegans) ; UNC13A
Background	UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.
Categories	Primary Antibodies
Cellular Localization	Cell Junction, Cytoplasm, Membrane, Synapse
Clonality	polyclonal
Description	UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.
Host	Rabbit
Immunogen	unc-13 homolog A(C. elegans)
Isotype	IgG
Molecular Weight	193 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cell junction, Cell membrane, Cytoplasm, Membrane, Synapse
Synonyms	KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A

Antigen	UNC13A/Munc13-1
Uniprot	Q9UPW8
Gene Id	23025
Research Area	Signal Transduction, Neuroscience
Weight	193kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000
IP	1:200-1:2000

Tested Application

WB: 1:500-1:5000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809244	FNab09255	100ug	$280		Add to Cart

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