It is envelope glycoprotein that forms spikes at the surface of virion envelope. UL27 is essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans.It is involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.It may be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress(By similarity). Also plays a role, together with gK, in virus-induced cell-to-cell fusion(syncytia formation).
Categories
Primary Antibodies
Clonality
polyclonal
Description
It is envelope glycoprotein that forms spikes at the surface of virion envelope. UL27 is essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans.It is involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.It may be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress (By similarity). Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).
Host
Rabbit
Immunogen
Envelope glycoprotein B
Isotype
IgG
Molecular Weight
69 kDa
Reactivity
Hsv
Regulatory
RUO
Synonyms
Envelope glycoprotein B,Gb
Antigen
UL27
Uniprot
P10211
Weight
69kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)