Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm, Nucleus
Clonality
polyclonal
Description
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Host
Rabbit
Immunogen
ubiquitin-conjugating enzyme E2E 3
Isotype
IgG
Molecular Weight
23 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm, Nucleus
Synonyms
UBE2E3, Ubiquitin carrier protein E3, UBCH9, UbcM2, UBCE4
Antigen
UBE2E3
Uniprot
Q969T4
Gene Id
10477
Research Area
Epigenetics, Metabolism
Weight
23kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)