Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N- methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
Host
Rabbit
Immunogen
tRNA-yW synthesizing protein 1 homolog B(non-protein coding)
Isotype
IgG
Molecular Weight
77 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
TYW1B, RSAFD2, NCRNA00069
Antigen
TYW1B
Uniprot
Q6NUM6
Gene Id
441250
Research Area
Metabolism
Weight
77kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)