This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
tripeptidyl peptidase II
Isotype
IgG
Molecular Weight
138 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
FLJ40359, TPP 2, TPP II, TPP2, TPPII, Tripeptidyl aminopeptidase, Tripeptidyl peptidase 2, Tripeptidyl peptidase II
Antigen
TPPII
Uniprot
P29144
Gene Id
7174
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)