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Home / Primary Antibodies / Polyclonal Antibodies

Toll-like receptor 8 Antibody / TLR8

SKU : BHA17122788

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NSJ Bioreagents

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Mfr.No.	RQ6527
Clonality	Polyclonal (rabbit origin)
Description	TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288).The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognizes G-rich oligonucleotides.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids RLQEVPQTVGKYVTELDL from the human protein were used as the immunogen for the Toll-like receptor 8 antibody.
Isotype	Rabbit IgG
Species Reactivity	Human
Note	Optimal dilution of the Toll-like receptor 8 antibody should be determined by the researcher.

Uniprot	Q9NR97

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the Toll-like receptor 8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 2-5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122788	RQ6527	100ug	$439		Add to Cart

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