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Home / Primary Antibodies / Polyclonal Antibodies

TMED5 Antibody / Transmembrane emp24 domain-containing protein 5

SKU : BHA17119140

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NSJ Bioreagents

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Mfr.No.	RQ6727
Cellular Localization	cytoplasmic, Nuclear
Clonality	Polyclonal (rabbit origin)
Description	Transmembrane emp24 domain-containing protein 5 is a protein that in humans is encoded by the TMED5 gene. TMED5 is a 229 amino acid single-pass type I membrane protein that belongs to the EMP24/GP25L family and contains one GOLD domain. The gene that encodes TMED5 contains nearly 31,000 bases and maps to human chromosome 1p22.1. As the largest human chromosome, chromosome 1 spans about 260 million base pairs and makes up approximately 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids D33-K164) was used as the immunogen for the TMED5 antibody.
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	TMED5
Uniprot	Q9Y3A6

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the TMED5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, IF, WB
Dilution	Western blot: 1-2ug/ml,Immunofluorescence (FFPE): 5ug/ml,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119140	RQ6727	100ug	$439		Add to Cart

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