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Home / Primary Antibodies / Polyclonal Antibodies

TLS Antibody / Translocated in liposarcoma protein / FUS

SKU : BHA17119281

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NSJ Bioreagents

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Mfr.No.	RQ6869
Cellular Localization	Nuclear
Clonality	Polyclonal (rabbit origin)
Description	RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Host	Rabbit
Immunogen Region	Amino acids ENVTIESVADYFKQ from the human protein were used as the immunogen for the TLS antibody.
Isotype	Rabbit IgG
Reactivity	Rat, Human, Mouse
Recombinant	No

Antigen	FUS
Uniprot	P35637

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the TLS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	FACS, IF, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119281	RQ6869	100ug	$439		Add to Cart

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