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Home / Primary Antibodies / Polyclonal Antibodies

TLR7 Antibody / Toll-like Receptor 7

SKU : BHA17104381

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NSJ Bioreagents

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Mfr.No.	R30823
Clonality	Polyclonal
Description	Toll-like receptor 7 is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. It is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human TLR7 (QAHPYFWQCLKNALATDNH) was used as the immunogen for this TLR7 antibody.
Isotype	Ig
Predicted Reactivity	Human, Rat, Mouse
Reactivity	Human, Rat, Mouse
Recombinant	No

Antigen	TLR7
Uniprot	Q9NYK1

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the TLR7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104381-1	R30823	100ug	$439		Add to Cart

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