MAPT, Microtubule-associated protein Tau, appears to be enriched in axons. The MAPT gene is assigned to chromosome 17 by hybridization of a cDNA clone to flow-sorted and spot-blotted chromosomes and to 17q21 by in situ hybridization, containing 16 exons. The Tau proteins are the product of alternative splicingfrom a single gene that in humans is designated MAPT. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons in the central nervous system and are less common elsewhere. When the proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimers disease.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Amino acids 29-44 (YTMHQDQEGDTDAGLK) were used as the immunogen for this Tau antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
Tau
Uniprot
P10636
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the Tau antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.