Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Required for ciliogenesis and sonic hedgehog/SHH signaling (PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (By similarity). Involved in regulation of cell intracellular organization (PubMed:26386247). Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (PubMed:25251415).
Host
Rabbit
Immunogen
KIAA0586
Isotype
IgG
Reactivity
Human, Mouse
Regulatory
RUO
Antigen
TALPID3
Uniprot
E9PV87
Gene Id
76967
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)