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Home / Primary Antibodies / Polyclonal Antibodies

Stefin B Antibody

SKU : BHA17104682

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NSJ Bioreagents

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Mfr.No.	R31218
Clonality	Polyclonal
Description	Cystatin B (CSTB), also called Stefin B (STFB), is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The gene is located on 21q22.3. The protein is widely distributed and is localized mostly intracellularly, but has been found extracellularly. It is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is though to be as a protector against the proteinases leaking from lysosomes. A STFB multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, STFB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of the protein is dependent on the differentiation status of the cell.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human Stefin B (QLEEKENKKFPVFKAVSFKS) was used as the immunogen for this Stefin B antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	Stefin B
Uniprot	P04080

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Stefin B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104682-1	R31218	100ug	$439		Add to Cart

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