SOX7 belongs to SOX gene family and member proteins are transcription factors with critical roles in the regulation of diverse developmental processes. In cotransfected 293 cells, SOX7 reduced <a href=../search_result.php?search_txt=wnt>Wnt</a>/<a href=../search_result.php?search_txt=catenin>beta-catenin</a> stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of human SOX7 (LISVLADATATYYNSYSVS) was used as the immunogen for this SOX7 antibody (100% homologous in human, mouse and rat).
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Antigen
SOX7
Uniprot
Q9BT81
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the SOX7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.