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Home / Primary Antibodies / Polyclonal Antibodies

Smad2 Antibody

SKU : BHA17104519

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NSJ Bioreagents

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Mfr.No.	R30998
Clonality	Polyclonal
Description	SMAD family member 2, also known as MADR2, and MADH2 (Mothers against decapentaplegic homolog 2), is a protein that in humans is encoded by the SMAD2 gene. It belongs to the SMAD family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene 'Sma.' The gene has been mapped to 18q21.1, a region which is frequently deleted in colorectal cancers. SMAD2 mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the N-terminus of human Smad2 (DQWDTTGLYSFSEQTRSLD) was used as the immunogen for this Smad2 antibody (100% homologous in human, mouse and rat).
Isotype	Ig
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Rat, Human, Mouse
Recombinant	No

Antigen	SMAD2
Uniprot	Q15796

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Smad2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB, ICC
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104519-1	R30998	100ug	$439		Add to Cart

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