Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
Host
Rabbit
Immunogen Region
Recombinant human protein (amino acids K34-N213) was used as the immunogen for the SLAMF1 antibody.
Isotype
Rabbit IgG
Reactivity
Human
Recombinant
No
Antigen
CD150
Uniprot
Q13291
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format
Antigen affinity purified
Purification
Antigen affinity purified
Storage
After reconstitution, the SLAMF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.