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Home / Primary Antibodies / Polyclonal Antibodies

SIRT1 Antibody

SKU : BHA17104960

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NSJ Bioreagents

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Mfr.No.	R31578
Clonality	Polyclonal
Description	Sirtuin 1, also known as SIR2L1, is a protein that in humans is encoded by the SIRT1 gene. Sirtuin 1 is a member of the sirtuin family of proteins, homologs of the Sir2 gene in S. cerevisiae. Family members are characterized by a sirtuin core domain and grouped into four classes. Sirtuin 1 is downregulated in cells that have high insulin resistance and inducing its expression increases insulin sensitivity, suggesting the molecule is associated with improving insulin sensitivity. Furthermore, SIRT1 was shown to de-acetylate and affect the activity of both members of the PGC1-alpha/ERR-alpha complex, which are essential metabolic regulatory transcription factors.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 112-311) was used as the immunogen for this SIRT1 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	SIRT1
Gene Id	23411

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the SIRT1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104960	R31578	100ug	$439		Add to Cart

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