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Home / Primary Antibodies / Polyclonal Antibodies

Sigma1-receptor Antibody / SIGMAR1

SKU : BHA17119314

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NSJ Bioreagents

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Mfr.No.	RQ6902
Cellular Localization	cell membrane, cytoplasmic, Nuclear
Clonality	Polyclonal (rabbit origin)
Description	The sigma-1 receptor, one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the sigma-1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids G1-H154) was used as the immunogen for the Sigma1-receptor antibody.
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat, Monkey
Recombinant	No

Antigen	Sigma1-receptor
Uniprot	Q99720

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the Sigma1-receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119314	RQ6902	100ug	$439		Add to Cart

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