Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Host
Rabbit
Immunogen
SH2 domain containing 4A
Isotype
IgG
Molecular Weight
48-50 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
PPP1R38, SH2A
Antigen
SH2D4A
Uniprot
Q9H788
Gene Id
63898
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)