Ribosomal Protein S6 Kinase, 90-KD, 1, also called RSK1, is an enzyme that in humans is encoded by the RPS6KA1 gene. The RSK(ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90(RSK). Homologs exist in several species. By analysis of somatic cell hybrids, Moller et al.(1994) mapped the gene to chromosome 3. Bonni et al.(1999) characterized the mechanism by which the RAS-MAPK signaling pathway mediates growth factor-dependent cell survival. Inoue et al.(2007) demonstrated that p90RSK, the kinase immediately downstream from Mos-MAPK, directly targets Erp1 for CSF arrest in Xenopus oocytes.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of human RSK1 (ILAQRRVRKLPSTTL) was used as the immunogen for this RSK1 antibody (100% homologous in human, mouse and rat).
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Antigen
RSK1
Uniprot
Q15418
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the RSK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.