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Home / Primary Antibodies / Polyclonal Antibodies

Ribosomal Protein S6 (phospho Ser235/S236) Rabbit pAb

SKU : BHA15206078

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ELK Biotechnology

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Mfr.No.	ES7077
Background	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS6 encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. 40S ribosomal protein S6 belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Clonality	Polyclonal
Host	Rabbit
Immunogen	Synthesized peptide derived from human Ribosomal Protein S6 around the phosphorylation site of S235/S236.
Isotype	IgG
Reactivity	Human, Mouse, Rat

Gene Id	6194

Concentration	1mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ELISA

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA15206078	ES7077	50µl	$148		Add to Cart
BHA15206078	ES7077	100µl	$248		Add to Cart

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