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Home / Primary Antibodies / Polyclonal Antibodies

PTPN11 Antibody (CSB-PA004086)

SKU : BHA10542845

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA004086
Alternative Names	PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3
Categories	Primary Antibodies
Host	Rabbit
Immunogen	Synthesized peptide derived from Human SH-PTP2 around the non-phosphorylation site of Y580.
Involvement In Disease	LEOPARD syndrome 1 (LPRD1); Noonan syndrome 1 (NS1); Leukemia, juvenile myelomonocytic (JMML); Metachondromatosis (MC)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Species	Homo Sapiens (Human)
Subcellular Location	Cytoplasm, Nucleus

Antigen	PTPN11
Uniprot	Q06124
Database Links	HGNC:9644 OMIM:151100 KEGG:hsa:5781 STRING:9606.ENSP00000340944 UniGene:Hs.506852
Function	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway
Pathway	Jak-STAT signaling pathway Ras signaling pathway Leukocyte transendothelial migration Natural killer cell mediated cytotoxicity Adipocytokine signaling pathway Phospholipase D signaling pathway Neurotrophin signaling pathway
Protein Families	Protein-tyrosine phosphatase family, Non-receptor class 2 subfamily
Tissue Specificity	Widely expressed, with highest levels in heart, brain, and skeletal muscle.

Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form	Liquid
Format	Liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications

WB, IHC, ELISA

Description

WB ; IHC ; ELISA, WB ; ELISA ; IHC

Dilution

WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:20000

Tested Application

WB,IHC,ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Datasheet
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10542845	CSB-PA004086	50ug	$119		Add to Cart
BHA10542845	CSB-PA004086	100ug	$199		Add to Cart

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