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Home / Primary Antibodies / Polyclonal Antibodies

PSMD8 Antibody / 26S proteasome non-ATPase regulatory subunit 8

SKU : BHA17119205

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NSJ Bioreagents

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Mfr.No.	RQ6792
Cellular Localization	nuclear, Cytoplasmic
Clonality	Polyclonal (rabbit origin)
Description	26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene. The 26S proteasome is a multi-catalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids A86-V350) was used as the immunogen for the PSMD8 antibody.
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	PSMD8
Uniprot	P48556

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the PSMD8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, IF, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119205	RQ6792	100ug	$439		Add to Cart

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