Plakoglobin Antibody / Gamma Catenin

Mfr.No.	R31599
Clonality	Polyclonal
Description	Junction Plakoglobin (JUP), also known as<a href=../search_result.php?search_txt=gamma>gamma-catenin</a>, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to<a href=../search_result.php?search_txt=beta><font face=symbol>b</font>-catenin</a>, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Additionally, Plakoglobin may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 556-745) was used as the immunogen for this Plakoglobin antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	Plakoglobin
Gene Id	3728

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Plakoglobin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	FACS, IF, ICC, IHC-F, IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml,Immunofluorescence (FFPE): 2-4ug/ml,Flow cytometry: 1-3ug/million cells