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Home / Primary Antibodies / Polyclonal Antibodies

PAK6 Antibody

SKU : BHA17104380

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NSJ Bioreagents

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Mfr.No.	R30819
Clonality	Polyclonal
Description	p21 protein-activated kinase 6 is an enzyme that in humans is encoded by the PAK6 gene. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding(CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor(AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the N-terminus of human PAK6 (QNFQHRVHTSFDPKEGK) was used as the immunogen for this PAK6 antibody (100% homologous in human, mouse and rat).
Isotype	IgG
Predicted Reactivity	Human, Rat, Mouse
Reactivity	Human, Rat, Mouse
Recombinant	No

Antigen	PAK6
Uniprot	Q9NQU5

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the PAK6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104380-1	R30819	100ug	$439		Add to Cart

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