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Home / Primary Antibodies / Polyclonal Antibodies

P-Cadherin Antibody / CDH3

SKU : BHA17119175

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NSJ Bioreagents

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Mfr.No.	RQ6762
Cellular Localization	cytoplasmic, Cell surface
Clonality	Polyclonal (rabbit origin)
Description	Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids Q236-E645) was used as the immunogen for the P Cadherin antibody.
Isotype	Rabbit IgG
Reactivity	Human
Recombinant	No

Antigen	P-Cadherin
Uniprot	P22223

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the P Cadherin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, IF, WB
Dilution	Western blot: 1-2ug/ml,Immunofluorescence (FFPE): 5ug/ml,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119175	RQ6762	100ug	$439		Add to Cart

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