Origin recognition complex subunit 5 is a protein that in humans is encoded by the ORC5 (ORC5L) gene. The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Amino acids HDHPPEYSADFYAAYINI from the human protein were used as the immunogen for the ORC5L antibody.
Isotype
Rabbit IgG
Species Reactivity
Human, Mouse, Rat, Monkey
Note
Optimal dilution of the ORC5L antibody should be determined by the researcher.
Uniprot
O43913
Format
Antigen affinity purified
Purity
Affinity purified
Storage
After reconstitution, the ORC5L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Applications
FACS, IF, WB
Description
Western blot: 1-2ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells