Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Amino acids YNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR of human OMG were used as the immunogen for the OMG antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Antigen
OMG
Uniprot
P23515
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the OMG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.