POU domain class 2 transcription factor 1, also known as OTF1 or Oct-1, is a protein that in humans is encoded by the POU2F1 gene. The transcription factor was among the first identified members of the POU transcription factor family. It has been found that the Oct-1 dimer formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1 , whereas dimers formed on the consensus MORE (more PORE) (ATGCATATGCAT) or on MOREs from immunoglobulin heavy chain promoters (AT(G/A)(C/A)ATATGCAA) failed to interact. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 11-240) was used as the immunogen for this Oct-1 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
1-OCT
Gene Id
5451
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the Oct-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
WB, IHC-P
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml