Histone-lysine N-methyltransferase NSD3 is an enzyme that in humans is encoded by the WHSC1L1 gene. This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described.
Host
Rabbit
Immunogen Region
Recombinant human protein (amino acids Q46-K1425) was used as the immunogen for the NSD3 antibody.
Isotype
Rabbit IgG
Reactivity
Human, Monkey
Recombinant
No
Antigen
NSD3
Uniprot
Q9BZ95
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format
Antigen affinity purified
Purification
Antigen affinity purified
Storage
After reconstitution, the NSD3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Applications
Direct ELISA, WB
Dilution
Western blot: 1-2ug/ml,Direct ELISA: 0.1-0.5ug/ml
Reviews of NSD3 Antibody / Nuclear SET domain-containing protein 3