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Home / Primary Antibodies / Polyclonal Antibodies

NRGN Antibody / Neurogranin

SKU : BHA17122762

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NSJ Bioreagents

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Mfr.No.	RQ6501
Clonality	Polyclonal (rabbit origin)
Description	Neurogranin is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived human protein (amino acids K11-K54) was used as the immunogen for the NRGN antibody.
Isotype	Rabbit IgG
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the NRGN antibody should be determined by the researcher.

Uniprot	Q92686

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the NRGN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, WB
Description	Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122762	RQ6501	100ug	$439		Add to Cart

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