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Home / Primary Antibodies / Polyclonal Antibodies

NRF1 Antibody / Nuclear Respiratory Factor 1

SKU : BHA17104557

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NSJ Bioreagents

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Mfr.No.	R31050
Clonality	Polyclonal
Description	Nuclear Respiratory Factor 1 is also known as Alpha-Pal. Efiok et al.(1994) identified genes containing NRF1-binding sequences and found that these could be classified either as cellular proliferation genes, or as genes regulating the growth-responsive metabolic pathways of energy transduction, translation, and replication. Virbasius and Scarpulla(1994) noted that the nuclear-encoded mitochondrial transcription factor<a href=http://www.nsjbio.com/search_result.php?search_txt=tfam>TFAM</a>contains potential binding sites for NRF1, NRF2(GABPA) and SP1 within the promoter region. With use of binding and electrophoretic mobility shift assays, DNase footprinting, and mutation analysis of recombinant proteins, they demonstrated specific and functional binding of<a href=http://www.nsjbio.com/search_result.php?search_txt=nrf1>NRF1</a>and<a href=http://www.nsjbio.com/search_result.php?search_txt=nrf2>NRF2</a>to the TFAM promoter region.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human Nuclear Respiratory Factor 1 (QHGREDLLYAFEDQQTQ) was used as the immunogen for this NRF1 antibody (100% homologous in human, mouse and rat).
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Rat, Human, Mouse
Recombinant	No

Antigen	NRF1
Uniprot	Q16656

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the NRF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB, ICC
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104557	R31050	100ug	$439		Add to Cart

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