NMYC interactor (NMI) is a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. NMI also interacts with all <a href=../search_result.php?search_txt=stat>STAT</a>s except <a href=../search_result.php?search_txt=stat2>STAT2</a> and augments STAT-mediated transcription in response to cytokines <a href=../search_result.php?search_txt=il2>IL2</a> and <a href=../search_result.php?search_txt=ifn gamma>IFN-gamma</a>. mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 2-307) was used as the immunogen for this NMI antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
NMI
Gene Id
9111
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the NMI antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
FACS, IF, IHC-P, WB
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunofluorescence (FFPE): 2-4ug/ml,Flow cytometry: 1-3ug/million cells