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Home / Primary Antibodies / Polyclonal Antibodies

NEDD4 Antibody

SKU : BHA17119303

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NSJ Bioreagents

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Mfr.No.	RQ6891
Cellular Localization	cell membrane, Cytoplasm
Clonality	Polyclonal (rabbit origin)
Description	E3 ubiquitin-protein ligase NEDD4, also known as neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4), is an enzyme that in humans is encoded by the NEDD4 gene. This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids M1-A736) was used as the immunogen for the NEDD4 antibody.
Isotype	Rabbit IgG
Reactivity	Rat, Human
Recombinant	No

Antigen	NEDD4
Uniprot	P46934

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the NEDD4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, IF, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119303	RQ6891	100ug	$439		Add to Cart

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