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Home / Primary Antibodies / Polyclonal Antibodies

NEAS Antibody / SPTAN1 / Alpha II Spectrin / Alpha Fodrin

SKU : BHA17119139

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NSJ Bioreagents

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Mfr.No.	RQ6726
Cellular Localization	Cytoplasmic
Clonality	Polyclonal (rabbit origin)
Description	Alpha II-spectrin, also known as Spectrin alpha chain, brain, Alpha II Spectrin and Alpha Fodrin is a protein that in humans is encoded by the SPTAN1 gene. Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids E1916-S2472) was used as the immunogen for the NEAS antibody.
Isotype	Rabbit IgG
Reactivity	Rat, Mouse, Human
Recombinant	No

Antigen	SPTAN1
Uniprot	Q13813

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the NEAS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, IF, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119139	RQ6726	100ug	$439		Add to Cart

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