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Home / Primary Antibodies / Polyclonal Antibodies

NALP3 Antibody (NLRP3)

SKU : BHA17104926

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NSJ Bioreagents

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Mfr.No.	R31539
Clonality	Polyclonal
Description	NLR Family, Pyrin domain containing 3, also known as CIAS1, CRYOPYRIN, NALP3 or PYPAF1, is a protein that in humans is encoded by the NLRP3 gene. It is mapped to 1q44. The encoded protein may play a role in the regulation of inflammation and apoptosis. Consistent with an essential role for NALP3 inflammasomes in antifungal immunity, it has been showed that deficient mice are hypersusceptible to C. albicans infection. Activation of the NLRP3 inflammasome in response to virus or to RNA was dependent upon lysosomal maturation and reactive oxygen species production in human cells. The inflammasome senses obesity-associated danger signals and contributes to obesity-induced inflammation and insulin resistance.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (21-194) was used as the immunogen for this NLRP3 / NALP3 antibody.
Isotype	Ig
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	NALP3
Gene Id	114548

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the NALP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104926	R31539	100ug	$439		Add to Cart

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