MyD88 is a cytosolic adapter protein that plays a central role in the<a href=../antibody_product_list.php?id=35>innate</a>and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and<a href=../tlr-toll-like-receptor-antibodies.html>Toll-like receptor</a>signaling pathways. Inhibiting the IL1R/MyD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 44-264) was used as the immunogen for this MyD88 antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Mouse, Rat, Human
Recombinant
No
Antigen
MyD88
Gene Id
4615
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
The MyD88 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
Applications
IHC-P, IF, WB, FACS
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunofluorescence: 1-3ug/ml,Flow cytometry: 1-3ug/million cells