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Home / Primary Antibodies / Polyclonal Antibodies

MyD88 Antibody

SKU : BHA17104325

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NSJ Bioreagents

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Mfr.No.	R30745
Clonality	Polyclonal
Description	Myeloid differentiation primary response gene 88 is a protein that in humans is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors(IL1Rs). It a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and<a href=../tlr-toll-like-receptor-antibodies.html>Toll-like receptor</a>signaling pathways. Qverexpression causes an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of the protein has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MyD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human MyD88 (FVQEMIRQLEQTNYR) was used as the immunogen for this MyD88 antibody.
Isotype	Ig
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	MyD88
Uniprot	Q99836

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the MyD88 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104325-1	R30745	100ug	$439		Add to Cart

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