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Home / Primary Antibodies / Polyclonal Antibodies

Menin Antibody

SKU : BHA17105047

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NSJ Bioreagents

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Mfr.No.	R31676
Clonality	Polyclonal
Description	The MEN1 gene encodes Menin, a nuclear scaffold protein that regulates gene transcription by coordinating chromatin remodeling. It is mapped to 11q13.1. MEN1 is considered to act as a tumor suppressor gene. It has been found that that MEN1 inactivation by antisense RNA antagonizes transforming growth factor-beta-mediated cell growth inhibition. Overexpression in an inducible cell culture system downregulated the proximal promoter. In vitro studies have shown that the protein is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD. Additionally, MEN1 was essential to maintain MLL-associated myeloid transformation.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 301-615) was used as the immunogen for this Menin antibody. Human MEN1 shares 93% and 94% amino acid sequence identity with mouse and rat, respectively.
Isotype	IgG
Predicted Reactivity	Human, Mouse
Reactivity	Mouse, Human
Recombinant	No

Antigen	Menin
Gene Id	4221

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Menin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105047	R31676	100ug	$439		Add to Cart

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