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Home / Primary Antibodies / Polyclonal Antibodies

MEKK2 Antibody

SKU : BHA17110741

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NSJ Bioreagents

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Mfr.No.	RQ6104
Clonality	Polyclonal
Description	MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase (MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	A human recombinant partial protein (amino acids M1-Q364) was used as the immunogen for the MEKK2 antibody.
Isotype	IgG
Predicted Reactivity	Human, Rat
Reactivity	Human, Rat
Recombinant	No

Antigen	MEKK2
Uniprot	Q9Y2U5

Format	Antigen affinity purified
Purification	Affinity purified
Storage	After reconstitution, the MEKK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	Direct ELISA, IF, WB
Dilution	Western blot: 1-2ug/ml,Immunofluorescence: 5ug/ml,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110741	RQ6104	100ug	$439		Add to Cart

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