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Home / Primary Antibodies / Polyclonal Antibodies

LXR alpha Antibody (NR1H3)

SKU : BHA17104051

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NSJ Bioreagents

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Mfr.No.	R30351
Clonality	Polyclonal
Description	Liver X receptor alpha, also called NR1H3, is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, Liver X receptor activity is critical for physiologic lipid metabolism and transport. They are endogenous inhibitors of atherogenesis and are targets for therapeutic intervention in cardiovascular disease. Furthermore, they and their ligands are negative regulators of macrophage inflammatory gene expression. Liver X receptors act as a transcriptional switch that integrates hepatic glucose metabolism and fatty acid synthesis. The LXR-IDOL-LDLR axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human LXR alpha (NVQDQLQVERLQHTY) was used as the immunogen for this LXR alpha antibody (100% homologous in human, mouse and rat).
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	LXR alpha
Uniprot	Q13133

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the LXR alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104051	R30351	100ug	$439		Add to Cart

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