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Home / Primary Antibodies / Polyclonal Antibodies

LRWD1 antibody

SKU : BHA10804859

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Mfr.No.	FNab04867
Alternative Names	CENP-33 ; ORCA
Background	Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Host	Rabbit
Immunogen	leucine-rich repeats and WD repeat domain containing 1
Isotype	IgG
Molecular Weight	85 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	CENP-33, ORCA

Antigen	LRWD1
Uniprot	Q9UFC0
Gene Id	222229
Research Area	Developmental biology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804859	FNab04867	100ug	$280		Add to Cart

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