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Home / Primary Antibodies / Polyclonal Antibodies

LIR-1 Antibody / LILRB1 / ILT-2

SKU : BHA17122753

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NSJ Bioreagents

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Mfr.No.	RQ6492
Clonality	Polyclonal (rabbit origin)
Description	Leukocyte immunoglobulin-like receptor subfamily B member 1 is a protein that in humans is encoded by the LILRB1 gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived human protein (amino acids Q347-Q442) was used as the immunogen for the LIR-1 antibody.
Isotype	Rabbit IgG
Species Reactivity	Human
Note	Optimal dilution of the LIR-1 antibody should be determined by the researcher.

Uniprot	Q8NHL6

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the LIR-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, FACS, Direct ELISA
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122753	RQ6492	100ug	$439		Add to Cart

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