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Home / Primary Antibodies / Polyclonal Antibodies

Lanosterol 14-alpha demethylase Antibody / CYP51A1

SKU : BHA17111052

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NSJ Bioreagents

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Mfr.No.	RQ6417
Clonality	Polyclonal
Description	P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYP51A1 (cytochrome P450, family 51, subfamily A, polypeptide 1), also known as LDM (lanosterol 14-alpha demethylase) or cytochrome P450-14DM, is a 503 amino acid protein localized to endoplasmic reticulum membrane. CYP51A1 is an important enzyme for zymosterol and steroid biosynthesis. CYP51A1 catalyzes C14-demethylation of lanosterol, transforming lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. CYP51A1 is ubiquitously expressed, with highest levels found in liver, ovary, testis, lung, kidney and prostate.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids K141-K503) was used at the immunogen for the Lanosterol 14-alpha demethylase antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Monkey
Reactivity	Mouse, Monkey, Human
Recombinant	No
Subcellular Location	Cytoplasmic

Antigen	Lanosterol 14-alpha demethylase
Uniprot	Q16850

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Format	Purified
Purification	Antigen affinity purified
Storage	After reconstitution, the Lanosterol 14-alpha demethylase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IF, FACS, WB, Direct ELISA
Dilution	Western blot: 0.5-1ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17111052	RQ6417	100ug	$439		Add to Cart

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