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Home / Primary Antibodies / Polyclonal Antibodies

LAMC2 Antibody / Laminin gamma 2

SKU : BHA17104262

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NSJ Bioreagents

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Mfr.No.	R30659
Clonality	Polyclonal
Description	Laminin subunit gamma-2 is a protein that in humans is encoded by the LAMC2 gene. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. This gene encodes the gamma chain isoform laminin, gamma2. The gamma2 chain, formerly though to be a truncated version of beta chain(B2t), is highly homologous to the gamma1 chain; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma1, and is specifically localized to epithelial cells in skin, lung and kidney. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of LAMC2 (ETSIDGILADVKNLENIRDNL) was used as the immunogen for this LAMC2 antibody (100% homologous in human, mouse and rat).
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	LAMC2
Uniprot	Q13753

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the LAMC2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104262-1	R30659	100ug	$439		Add to Cart

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