Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Host
Rabbit
Immunogen
potassium inwardly-rectifying channel, subfamily J, member 15
Isotype
IgG
Molecular Weight
35 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KCNJ14
Antigen
KCNJ15
Uniprot
Q99712
Gene Id
3772
Research Area
Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)