Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
A human recombinant partial protein (amino acids M1-V495) was used as the immunogen for the KCNA1 antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Rat, Human, Mouse
Recombinant
No
Antigen
Kv1.1
Uniprot
Q09470
Format
Antigen affinity purified
Purification
Affinity purified
Storage
After reconstitution, the KCNA1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
FACS, WB, Direct ELISA
Dilution
Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml